Resumen: Platelet-rich plasma (PRP) is the volume of autologous plasma containing a high concentration of platelets plus growth factors and fibrin that help in rapid wound healing. Multiple cases of its use have been reported in different animal species, both domestic and wild; however, the protocols for obtaining it are very diverse, which makes it difficult to compare results and determine the quality of the plasma produced. The aim of this review was to establish the main differences in the PRP preparation protocols for domestic and wild animals. The information was obtained from databases and search engines. In total, 49 procedures were retrieved and 31 used sodium citrate as an anticoagulant. Most of the works were carried out on horses (n=21). Platelet concentrations in bovines vary significantly between individuals, presenting a wider range of values, while in horses a lower dispersion of the data is observed. Double centrifugation was used in 67% of the studied, with the speed of the second centrifugation generally being higher than the first. The centrifugation time did not change substantially between the two centrifugations.